PittsburghV1, Main, Exploration, bibRecord, 000216

Muscle Extracellular Matrix Scaffold Is a Multipotent Environment

Identifieur interne : 000216 ( Main/Exploration ); précédent : 000215; suivant : 000217

Muscle Extracellular Matrix Scaffold Is a Multipotent Environment

Auteurs : Paola Aulino [Italie] ; Alessandra Costa [États-Unis] ; Ernesto Chiaravalloti [Italie] ; Barbara Perniconi [France] ; Sergio Adamo [Italie] ; Dario Coletti [Italie] ; Massimo Marrelli [Italie] ; Marco Tatullo [Italie] ; Laura Teodori [Italie]

Source :

International Journal of Medical Sciences [ 1449-1907 ] ; 2015.

RBID : Hal:hal-01270966

English descriptors

mix :
- ECM scaffold, bone, cartilage, skeletal muscle, tissue engineering.

Abstract

The multipotency of scaffolds is a new concept. Skeletal muscle acellular scaffolds (MAS) implanted at the interface of Tibialis Anterior/tibial bone and masseter muscle/mandible bone in a murine model were colonized by muscle cells near the host muscle and by bone-cartilaginous tissues near the host bone, thus highlighting the importance of the environment in directing cell homing and differentiation. These results unveil the multipotency of MAS and point to the potential of this new technique as a valuable tool in musculo-skeletal tissue regeneration.

Url:

http://hal.upmc.fr/hal-01270966

DOI: 10.7150/ijms.10761

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Hal, to step Corpus: 000397
to stream Hal, to step Curation: 000397
to stream Hal, to step Checkpoint: 000181
to stream Main, to step Merge: 000216
to stream Main, to step Curation: 000216

Le document en format XML

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<front><div type="abstract" xml:lang="en">The multipotency of scaffolds is a new concept. Skeletal muscle acellular scaffolds (MAS) implanted at the interface of Tibialis Anterior/tibial bone and masseter muscle/mandible bone in a murine model were colonized by muscle cells near the host muscle and by bone-cartilaginous tissues near the host bone, thus highlighting the importance of the environment in directing cell homing and differentiation. These results unveil the multipotency of MAS and point to the potential of this new technique as a valuable tool in musculo-skeletal tissue regeneration.</div>
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Serveur d'exploration sur Pittsburgh

Muscle Extracellular Matrix Scaffold Is a Multipotent Environment

Muscle Extracellular Matrix Scaffold Is a Multipotent Environment

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